Study finds possible link between long Covid and childhood hepatitis

Experts warn that the results do not fully explain the medical mystery behind the global outbreak of childhood hepatitis. Separately, the Centers for Disease Control and Prevention has reported that childhood hepatitis rates in the United States are not necessarily higher than before the pandemic.

ABC News: Study of childhood hepatitis cases points to previous COVID infection, but experts say it’s too early to know

A new study points to a previous COVID-19 infection as a possible culprit for the global spate of severe hepatitis cases in children – although experts warn the real cause remains a medical mystery. Researchers in Israel added evidence for the theory in a small study published in the Journal of Pediatric Gastroenterology and Nutrition, suggesting that some children may develop liver inflammation within weeks of recovering from mild COVID-19 infection. . (Salzman, 6/14)

The Jerusalem Post: Long COVID May Cause Mysterious Childhood Hepatitis – Study

The long COVID may be the cause of unexplained cases of hepatitis in children around the world in recent months, Israeli researchers from Schneider Children’s Medical Center, Rabin Medical Center – Beilinson Hospital, Rambam Medical Center and the Tel Aviv University in a study recently published in the peer-reviewed Journal of Pediatric Gastroenterology and Nutrition. … The Israeli scientists who conducted the study noted that liver damage has been recorded in adult patients with severe coronavirus infections and that children may have multisystem inflammatory syndrome (MIS-C) as a result COVID-19, which can injure the liver. Post-COVID-19 liver damage has also been increasingly reported in adults. (Joffre, 6/14)

Learn more about the hepatitis epidemic —

The New York Times: Unexplained hepatitis no more common in American children than before pandemic, suggests CDC

Unexplained hepatitis does not appear to have become more common among American children than it was before the start of the Covid-19 pandemic, according to a new review of three major medical databases by researchers from the Centers for Disease Control and Prevention. The findings are part of an ongoing investigation into a puzzling cluster of cases of severe hepatitis, or inflammation of the liver, in previously healthy children, dating back to October 2021. As of May 26, 650 probable cases had been reported in 33 countries, according to the World Health Organization. Although cases are extremely rare, they can be serious, resulting in liver transplants or death. (Anthes, 6/14)

In other long covid news —

Newsday: Study: Chronically ill 9/11 responders may become more severe at COVID-19

According to a new study from the Stony Brook World Trade Center Health and Wellness Program, World Trade Center responders with chronic health conditions who contract COVID-19 may have more severe, long-term illness from the virus. The study looked at 1,280 patients in the program with COVID-19, all of whom were 9/11 responders, comparing those who had a chronic condition to those who did not. It was published this month in the International Journal of Environmental Research and Public Health. (Colangelo, 6/13)

Weather: Dogs Can Sniff Out COVID-19 and Signs of Long COVID

Dogs can also detect viral compounds in the sweat of Long COVID patients up to 18 months after first catching the virus, according to a study co-authored by Grandjean and published in January on MedRxiv, a server for new research that has not yet been peer reviewed. (The study was later published in the Journal of Clinical Trials.) Canines in this study detected evidence of the virus in samples from 23 of 45 Long COVID patients in the trial, but not among sweat samples from of 188 people. without Long COVID. (Ducharme, 6/14)

Nature: How months-long COVID infections could seed dangerous new variants

Virologist Sissy Sonnleitner is tracking nearly all COVID-19 cases in Austria’s rugged East Tyrol region. So when a woman there continued to test positive for months, Sonnleitner was determined to figure out what was going on. Before being infected with SARS-CoV-2 in late 2020, the woman, who was in her 60s, was taking immunosuppressive drugs to treat a relapse of lymphoma. The COVID-19 infection persisted for more than seven months, causing relatively mild symptoms including fatigue and a cough. (Callaway, 6/15)

Time: Why so many long-term COVID patients have suicidal thoughts

Last year, Diana Berrent – the founder of Survivor Corps, a Long COVID support group – asked members of the group if they had ever had suicidal thoughts since the development of Long COVID. About 18% of people who responded said they had, a number well above the 4% of the general American adult population who had recently had suicidal thoughts. A few weeks ago, Berrent posed the same question to current members of his group. This time, of nearly 200 people who responded, 45% said they had considered suicide. (Ducharme, 6/13)

Fierce Biotech: Long COVID, Brief Dream: Phase 2 flop triggers end of PureTech bid to treat coronavirus complications

PureTech Health’s lengthy COVID trial failed. The drug candidate did not help patients with the disease walk further, prompting the company to drop plans for additional studies in the indication. In 2020, PureTech identified an opportunity to use its deuterated form of pirfenidone — a treatment for idiopathic pulmonary fibrosis that Roche’s Genentech sells as Esbriet — in patients with long COVID. The decision to start a clinical trial of the candidate, LYT-100, in the indication was supported by evidence of the prevalence of pulmonary fibrosis in COVID-19 patients and long-term symptom persistence. (Taylor, 6/14)

This is part of the KHN Morning Briefing, a summary of health policy coverage from major news outlets. Sign up for an email subscription.

Comments are closed.